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Large Language Models in Molecular Biology

Deciphering the language of biology, from DNA to cells to human health

Introduction

Will we ever decipher the language of molecular biology?

Here, I argue that we are just a few years away from having accurate in silico models of the primary biomolecular information highway — from DNA to gene expression to proteins — that rival experimental accuracy and can be used in medicine and pharmaceutical discovery.

Since I started my PhD in 1996, the computational biology community had embraced the mantra, “biology is becoming a computational science.”

Our ultimate ambition has been to predict the…

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